InFrame Synapse
A Robust and Scalable Solution for End-to-End High-Tech Manufacturing
The All-in-One Solution for Discrete Manufacturing
Discrete manufacturers must accelerate production ramp-up, maintain high quality and yield, and optimize operational costs to stay competitive. InFrame Synapse offers a powerful, scalable solution tailored to meet these demands, particularly for small and medium-sized enterprises (SMEs). As a comprehensive product family, it includes InFrame Synapse MES for production execution and InFrame Synapse EQC for seamless equipment integration, creating a fully connected digital infrastructure for discrete manufacturing.

InFrame Synapse MES
InFrame Synapse EQC
The Compact and Scalable MES Solution for Seamless Integration
InFrame Synapse MES is a powerful and adaptable Manufacturing Execution System (MES) designed to meet the unique needs of high-tech fabrication sites. With its modular and scalable architecture, it supports discrete manufacturing processes effortlessly, streamlining production planning, monitoring, and control. Its open architecture and Service-Oriented Architecture (SOA) enable seamless integration with existing IT systems, ensuring an efficient transition to IT-based manufacturing solutions both on the shop floor and at the ERP level.
Core Functions
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Complete product genealogy traceability – from raw to finished goods
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Integrated workflow engine to support different business processes
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Built-in audit trails for master data and transaction data
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Unique industry-specific version driven by industry
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Seamless GMP compliance and data integrity with ALCOA+ principles' data collection framework
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Fast and easy OpenAPI
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Built-in Application Performance Monitoring (APM)

Improved InFrame Synapse MES
Upgrade to InFrame Synapse MES 6 to experience a range of exciting new features, enhancements, and visible improvements, including Engineering State V1, Multi-Chamber Processing, Data Collection Plan Context Map – Perspective, REST API Enhancements, and more, all designed to facilitate a seamless transition from engineering to production, manage equipment with multiple chambers independently, as well as support a mature and robust production environment.
InFrame Synapse MES 6
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REST API Integration – More flexibility, automation, and scalability
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Engineering State – Safely test master-data changes in isolation
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Media Manager – Upload and manage processing-related media files
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APM Module – Centralized system monitoring and log analysis
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Process Plan Enhancements – Alternative routes, rework routes, time coupling
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Multi-Chamber Processing – Independently manage multi-chamber equipment
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LTS Ready (6.19) – Long-term support for stability and extended updates

Your Benefits at a Glance
InFrame Synapse MES provides a complete suite of advantages tailored to high-performance manufacturing. From accelerating production ramp-ups and enhancing yield quality to ensuring regulatory compliance and reducing operational costs, it empowers manufacturers to achieve efficiency and excellence across every stage of production.
Faster Production Ramp-up
By optimizing line logistics and offering pre-configured equipment interfaces, manufacturers can reduce the time it takes to transition from lab-scale to mass production, accelerating time to market.Improved Yield and Quality
InFrame Synapse MES ensures comprehensive data collection during the production process, allowing for precise analytics and diagnostic tools. These features enable manufacturers to continuously improve product quality and reduce waste, resulting in higher yields.Guaranteed Compliance
The platform offers complete tracking and tracing capabilities that ensure regulatory compliance in highly controlled industries such as medical devices and semiconductors. This allows manufacturers to meet strict industry standards without compromising production speed or quality.Lower Operational Costs
By optimizing key operational factors—cycle times, throughput, and Work-in-Progress (WIP)—InFrame Synapse MES minimizes operational expenses. Real-time monitoring helps reduce inefficiencies, allowing for smoother production cycles and more predictable outcomes.“Designed to handle complex process flows, high automation variability, and 24/7 operational demands, InFrame Synapse MES ensures reliability, high-volume data collection, and centralized deployment. It's the ideal choice for SMEs seeking cost-effective solutions that grow with their requirements.”
— Danny Yeoh, VP Business Development & Customer Success
A Powerful Interface for Easy System Integration
The InFrame Synapse Equipment Connector (EQC) enables OEMs to effortlessly add data interfaces to nearly any equipment PLC. Examples of commonly used interfaces include SEMI SECS/GEM, SEMI PV02, and CONTINENTAL GHP. No in-depth knowledge of the underlying protocols or architecture is required for PLC programmers. Configuration and documentation are streamlined through a single Excel spreadsheet, where PLC function blocks, configurations, and documentation can be generated with just a click of a button.
Key Capabilities
Supports All Major PLCs
InFrame Synapse EQC is compatible with all major Programmable Logic Controllers (PLCs), ensuring smooth integration with diverse equipment across manufacturing systems.Compliant with All Major Interface Standards
Including SEMI SECS/GEM (200mm and 300mm standards), SEMI-PV02, and other industrial protocols. InFrame Synapse EQC meets the highest standards for communication and interoperability.Compatible with Various Integration Methods
InFrame Synapse EQC supports a wide range of integration methods, including XML, JDBC, CSV, C, C++, .NET, GHP, and SECS/GEM, ensuring flexibility and adaptability for different system architectures.Easy to Use, Even for Non-IT Experts
Its intuitive configuration process allows users to set up and document equipment integration with minimal technical expertise. Tasks such as generating PLC function blocks, configurations, and documentation are streamlined through user-friendly tools like Excel spreadsheets.
Take the Next Step in Transforming Your Manufacturing Operations
Transform your manufacturing operations with a powerful one-stop customizable solution designed to meet your needs. Enhance efficiency, ensure compliance, and seamlessly scale your production. Contact us to discover how InFrame Synapse can accelerate your digital transformation.
Applications of InFrame Synapse MES:
Supporting Industries from SMEs to Global Manufacturers

MES for Battery Manufacturing: Maximizing Production Efficiency and Yield
The global shift towards net-zero emissions has driven a surge in EV adoption, creating unprecedented demand for batteries and straining supply chains. The rise of ‘Battery-as-a-Service’ (BaaS) is further reshaping the industry with quick battery swapping, promoting wider EV usage. To meet this growing demand, automakers are collaborating with energy sectors, while battery manufacturers focus on scaling production, innovating, and building gigafactories.

MES for Medical Devices: Ensuring Quality, Compliance, and Cost Efficiency
Medical device manufacturers face evolving regulations, the need for top-quality products, and complex global supply chains. Advanced technologies are replacing paper-based methods, enabling manufacturers to integrate innovative practices while maintaining cost-effectiveness, high safety standards, and regulatory compliance.
“InFrame Synapse is a centralized solution that serves as a single source of truth to optimize discrete manufacturing. With its advanced MES and seamless equipment integration, it ensures efficient track and trace, high quality, and continuous innovation across high-tech industries.”
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